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Gary Goldberg Selected Research

GEM231

3/2006A phase I safety and dose escalation trial of docetaxel combined with GEM231, a second generation antisense oligonucleotide targeting protein kinase A R1alpha in patients with advanced solid cancers.
9/2003A safety study of a mixed-backbone oligonucleotide (GEM231) targeting the type I regulatory subunit alpha of protein kinase A using a continuous infusion schedule in patients with refractory solid tumors.

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Gary Goldberg Research Topics

Disease

8Neoplasms (Cancer)
11/2011 - 09/2003
3Carcinoma (Carcinomatosis)
01/2006 - 03/2002
2Febrile Neutropenia
11/2011 - 03/2006
2Fatigue
03/2006 - 09/2003
1COVID-19
01/2022
1Inflammation (Inflammations)
01/2022
1Adenocarcinoma
08/2021
1Brain Injuries (Brain Injury)
01/2017
1Fever (Fevers)
11/2011
1Renal Cell Carcinoma (Grawitz Tumor)
11/2011
1Neutropenia
11/2011
1Prostatic Neoplasms (Prostate Cancer)
11/2011
1Hernia (Hernias)
09/2010
1Inguinal Hernia (Direct Inguinal Hernia)
09/2010
1Breast Neoplasms (Breast Cancer)
06/2007
1Ovarian Neoplasms (Ovarian Cancer)
02/2006
1Ovarian Epithelial Carcinoma
02/2006
1Lymphoma (Lymphomas)
01/2006
1Uterine Cervical Neoplasms (Cancer of the Cervix)
04/2004
1Residual Neoplasm
09/2003
1Warts (Wart)
09/2003
1Traumatic Brain Injuries (Traumatic Brain Injury)
07/2003
1Wounds and Injuries (Trauma)
07/2003
1Disease Progression
06/2003
1Endometrial Neoplasms (Endometrial Cancer)
06/2003
1Squamous Cell Neoplasms (Squamous Cell Cancer)
03/2002

Drug/Important Bio-Agent (IBA)

2GEM231IBA
03/2006 - 09/2003
2Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
03/2006 - 09/2003
2Cisplatin (Platino)FDA LinkGeneric
02/2006 - 04/2004
2Topotecan (Hycamtin)FDA LinkGeneric
02/2006 - 06/2003
1Famotidine (Pepcid)FDA LinkGeneric
01/2022
1SolutionsIBA
01/2017
1Vinorelbine (Navelbine)FDA LinkGeneric
11/2011
1Prostate-Specific Antigen (Semenogelase)IBA
11/2011
1Ketoconazole (Nizoral)FDA LinkGeneric
05/2008
1Pharmaceutical PreparationsIBA
05/2008
1ixabepilone (BMS 247550)FDA Link
05/2008
1Cytochrome P-450 CYP3AIBA
05/2008
1Capecitabine (Xeloda)FDA Link
06/2007
1EsterasesIBA
06/2007
1Irinotecan (Camptosar)FDA LinkGeneric
06/2007
1Docetaxel (Taxotere)FDA Link
03/2006
1Antisense OligonucleotidesIBA
03/2006
1Transaminases (Aminotransferases)IBA
03/2006
1GemcitabineFDA Link
01/2006
1LactonesIBA
04/2004
1Protein Kinase CIBA
04/2004
1OligonucleotidesIBA
09/2003
1Topoisomerase I InhibitorsIBA
06/2003
1Progestins (Progestagens)IBA
06/2003
1Hydroxyurea (Hydrea)FDA LinkGeneric
03/2002

Therapy/Procedure

6Therapeutics
11/2011 - 06/2003
3Drug Therapy (Chemotherapy)
06/2007 - 09/2003
3Radiotherapy
09/2003 - 03/2002
2Brachytherapy
08/2021 - 03/2002
1Herniorrhaphy
09/2010
1Prostatectomy (Retropubic Prostatectomy)
09/2010
1Intravenous Infusions
01/2006
1Patient Discharge
07/2003
1Length of Stay
07/2003